Author

Scott R. Walsh

University of GuelphORCID 0000-0002-8477-2985Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

Brian Dennis LichtyiD· 1 shared Christopher L. BakeriD· 1 shared Christopher M. SilvestriiD· 1 shared Claire G. Morris· 1 shared Derek T. CummingsiD· 1 shared Joanne A. HammilliD· 1 shared John C. Bell· 1 shared Jonathan L. BramsoniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Brian Dennis LichtyORCID

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1 paper

Recent·Most cited

Boosting of CAR-T cells with rhabdovirus is limited by type I interferon and rapid contraction

Rebecca Burchett, Claire G. Morris, Mira Ishak, Derek T. Cummings, Christopher L. Baker, Ricardo M. Marius, Natasha Kazdhan, Christopher M. Silvestri, John C. Bell, Brian Dennis Lichty, Scott R. Walsh, Yonghong Wan, Joanne A. Hammill, Jonathan L. Bramson

This study shows that boosting CAR-T cells with a VSV vaccine encoding the CAR-target leads to robust expansion but rapid contraction, while TCR-mediated boosting improves persistence and tumor eradication.

bioRxiv · Nov 29, 2024 · PreprintImmunology