Author

Kelvin Li

University of California, BerkeleyORCID 0000-0002-8483-9166Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Kelvin Li2 papers · Tan Tock Seng Hospital

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Daniel K. NomuraiD· 2 shared Thomas J. MaimoneiD· 2 shared Alicia Zhang· 1 shared Aman ModiiD· 1 shared Bhavna Malik· 1 shared Brynne Currier· 1 shared Christian E. StiegeriD· 1 shared Diana C. Beard· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

Daniel K. NomuraORCID

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2 papers

Recent·Most cited

Stereoselective Covalent Inhibitor of the Ovarian Cancer-Driving Transcription Factor PAX8

Taylor M Nuttall, Aman Modi, Kelvin Li, Emily A. Lau, Alicia Zhang, Bhavna Malik, Tezcan Güney, John E. Eksterowicz, Gregory T. Notte, Thomas J. Maimone, Daniel K. Nomura

This paper develops a stereoselective covalent inhibitor of PAX8, a key ovarian cancer driver, showing its ability to reduce PAX8 abundance and suppress its transcriptional program.

bioRxiv · Aug 21, 2026 · PreprintBiochemistry

Sulfinyl Aziridines as Stereoselective Covalent Destabilizing Degraders of the Oncogenic Transcription Factor MYC

Hannah T. Rosen, Kelvin Li, Christian E. Stieger, Erin L. Li, Brynne Currier, Scott M. Brittain, Francisco J. Garcia, Diana C. Beard, Michael D. Jones, Sandra Haenni‐Holzinger, Dustin Dovala, Jeffrey M. McKenna, Markus Schirle, Thomas J. Maimone, Daniel K. Nomura

This paper identifies a sulfinyl aziridine compound that selectively degrades MYC by targeting specific residues in its intrinsically disordered regions, demonstrating the potential of chiral small molecules for targeting undruggable proteins.

Angewandte Chemie International Edition · Sep 25, 2025Peer-reviewedCancer Biology