Anna Letizia Allegra Mascaro

Disrupted cortex-wide dynamics impair motor planning in Shank3-mutant mice

This study shows that Shank3 mutations disrupt cortex-wide dynamics, leading to impaired motor planning in mice.

All-Optical Mapping Reveals Distributed Suppression of Cortical Sensory Responses After Optogenetic Silencing

The paper develops an all-optical system to inhibit cortical neurons and monitor responses, showing widespread suppression of sensory responses after optogenetic silencing.

Altered cortical network in Parkinson's Disease: the central role of PV interneuron and synaptic remodelling

This study investigates cortical network disruptions in Parkinson's disease using a mouse model, finding PV interneuron dysfunction drives maladaptive plasticity and motor deficits.

Age-Dependent Cortical Overconnectivity in Shank3 Mice is Reversed by Anesthesia

The paper evaluates functional connectivity in Shank3b mice across ages and brain states, finding age-dependent hyperconnectivity that is anesthesia-sensitive.

Combining Gamma Neuromodulation and Robotic Rehabilitation Restores Parvalbimin-mediated Gamma Function and Boosts Motor Recovery in Stroke Mice

This study combines gamma neuromodulation and robotic rehabilitation to restore gamma function and improve motor recovery in stroke mice.

Frequency-Dependent Inter-Brain Synchrony is Modulated by Social Interaction in Freely Moving Mice

This paper introduces a new platform for hyperscanning in freely moving mice to study inter-brain synchrony during social interaction, finding frequency-dependent synchronization across the cortex.

Cortical mapping of the sensory response reveals strong brain-state dependence of the late component

This study shows that anesthesia levels affect the spatiotemporal features and functional connectivity of sensory-evoked responses in the mouse cortex, with the late component persisting under anesthesia.

Large-scale all-optical dissection of motor cortex connectivity reveals a segregated functional organization of mouse forelimb representations

The paper uses all-optical methods in awake mice to reveal a segregated functional organization of forelimb representations in the motor cortex, identifying a new lateral grasping area.

A distributed neocortical action map associated with reach-to-grasp

The paper uses calcium imaging to study neocortical dynamics during reach-to-grasp tasks in mice, revealing distributed and localized neural activity patterns.

Cortical propagation as a biomarker for recovery after stroke

This study identifies spatiotemporal propagation indicators from cortical activity in mice to track stroke-induced motor deficits and recovery across different rehabilitation paradigms.

Experimental and computational study on motor control and recovery after stroke: towards a constructive loop betweenexperimental and virtual embodiedneuroscience

This study integrates experimental and computational models of motor control and recovery after stroke to improve experimental design through continuous data integration and simulation.

Restoration of motor-evoked cortical activity is a distinguishing feature of the most effective rehabilitation therapy after stroke

This study identifies that combined optogenetic stimulation and motor training restores pre-stroke motor-evoked cortical activity, distinguishing it as the most effective post-stroke rehabilitation therapy.

Rehabilitation promotes the recovery of structural and functional features of healthy neuronal networks after stroke

Wide-field imaging of cortical neuronal activity with red-shifted functional indicators during motor task execution

The paper evaluates red-shifted GECIs for in vivo imaging of cortical neuronal activity during motor tasks in mice, finding jRCaMP1a suitable for longitudinal monitoring.

Whole-brain vasculature reconstruction at the single capillary level

This paper introduces a method to reconstruct whole-brain vasculature at the single capillary level using CLARITY, vascular staining, and light-sheet fluorescence microscopy.

Rehabilitation promotes the recovery of functional and structural features of healthy neuronal networks after stoke

This study shows rehabilitation promotes recovery of both structural and functional features of healthy neuronal networks after stroke in mice.