Simona Capsoni

This study analyzes mutations in neural signaling pathways across cancers, finding 65% of patients have alterations linked to poor survival and complex pathway interactions.

This paper identifies a NGF variant that selectively biases TrkA signaling towards neurotrophic functions without triggering pain, revealing mechanisms for therapeutic targeting of the NGF-TrkA pathway.

This study investigates cortical network disruptions in Parkinson's disease using a mouse model, finding PV interneuron dysfunction drives maladaptive plasticity and motor deficits.

This study investigates how congenital pain insensitivity in heterozygous humans and mice affects affective pain responses, finding dissociated effects on learned fear and neural processing.