Cancer BiologybioRxivPreprint
Ribonucleotide Reductase Inhibition Overcomes FLT3 Inhibitor Resistance in Acute Myeloid Leukemia
Zhen Tian, Xiaoyu Wei, Srinivas Chatla…·Jian Yuan Huang
This paper identifies RNR inhibition as a strategy to overcome FLT3 inhibitor resistance in FLT3ITD+ AML by reversing resistance mechanisms and enhancing therapeutic efficacy.
DOI 10.64898/2026.07.21.736123