Author

Klara Henrike Frahnert

Universitätsmedizin GöttingenORCID 0000-0002-8510-2502Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Carolin SchneideriD· 1 shared Constanza Tapia ContrerasiD· 1 shared Elisabeth HeßmanniD· 1 shared Günter SchneideriD· 1 shared Maj-Britt PaulsohniD· 1 shared Matthias DobbelsteiniD· 1 shared Xin Fang· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Carolin SchneiderORCID

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1 paper

Recent·Most cited

Simultaneous Targeting of KRAS and CDK4 Synergistically Suppresses Pancreatic Cancer Cells

Maj-Britt Paulsohn, Klara Henrike Frahnert, Xin Fang, Carolin Schneider, Constanza Tapia Contreras, Günter Schneider, Elisabeth Heßmann, Matthias Dobbelstein

This study shows that combining KRAS and CDK4/6 inhibitors synergistically suppresses pancreatic cancer cells and organoids with KRAS mutations, with durable effects even after drug washout.

bioRxiv · Jan 11, 2025 · PreprintCancer Biology