Günter Schneider

This study identifies LOY as a driver of aggressive PDAC through epigenetic reprogramming, linking it to EMT and metastasis, and highlights its clinical relevance as a biomarker.

This study uses an in ovo model to show that the CAM platform supports tumor-stroma coevolution in pancreatic cancer, preserving patient-specific features and enabling functional analysis of stromal interactions.

This paper generates cross-species single-cell atlases of pancreatic cancer to study progression, therapy response, and immune evasion across human and mouse models.

This study shows HDAC1 and HDAC2 protect BCR-ABL-positive CML cells from replication stress-induced apoptosis via the p73-NOXA axis.

micro_sam finetunes Segment Anything into a light microscopy generalist and a cell/neurite-focused electron microscopy model, plus napari tools for interactive 2d, volumetric and tracking annotation.

This study shows that combining KRAS and CDK4/6 inhibitors synergistically suppresses pancreatic cancer cells and organoids with KRAS mutations, with durable effects even after drug washout.