Cancer BiologybioRxivPreprint
Simultaneous Targeting of KRAS and CDK4 Synergistically Suppresses Pancreatic Cancer Cells
Maj-Britt Paulsohn, Klara Henrike Frahnert, Xin Fang…·Matthias Dobbelstein
This study shows that combining KRAS and CDK4/6 inhibitors synergistically suppresses pancreatic cancer cells and organoids with KRAS mutations, with durable effects even after drug washout.
2 citations