Walter J. Koch

The paper identifies and characterizes small molecule allosteric modulators of the AT1R, revealing their conformational mechanisms and effects on G protein and β-arrestin pathways.

This paper identifies SCoR2 as a denitrosylase that reprograms metabolism to protect the heart after myocardial infarction, showing reduced expression in human cardiomyopathy.

This study shows that inhibiting GSK-3β in cardiomyocytes promotes cardiac progenitor cell proliferation and improves cardiac function after myocardial infarction through paracrine signaling.