Donal J Cox

This study shows human macrophages secrete both interferon α and β during Mtb infection, challenging previous assumptions about their kinetics and timing.

This study shows dexamethasone reduces glycolysis in human macrophages but enhances mycobacterial killing, suggesting a potential therapeutic benefit in tuberculosis.

This study shows that human airway macrophages reprogram their metabolism in response to IFN-γ, leading to glycolysis-dependent functional plasticity that differs from monocyte-derived macrophages.