Ruiqi Ge

RNA accessibility sequencing reveals transcriptome-wide RBP binding and RNA structure

This paper introduces RAD-seq, a method to quantify RNA accessibility by protein binding, and shows it can detect RBP footprints and RNA structure changes under stress.

Single-nucleotide resolution mapping of m6A of zebrafish mRNAs in early embryonic development links m6A modifications to the maternal-to-zygotic transition

The paper maps m6A modifications in zebrafish embryos at single-nucleotide resolution, showing a significant decrease during maternal-to-zygotic transition.

N6-methyladenosine regulation of mRNA translation is essential for early human erythropoiesis

This study identifies two critical m6A-regulated developmental windows in human erythropoiesis, showing m6A-MTase activity is essential for proliferation and differentiation in BFU-E and CFU-E.

Catch and release of sialoglycoRNAs enables sequencing-based profiling across cellular and extracellular material

The paper introduces rPAL-seq, a method for profiling sialoglycoRNAs with low RNA input, revealing lineage-associated patterns and secreted glycoRNA profiles.