Ashley N. Plumb

The paper shows that antibiotics like β-lactams, macrolides, and tetracyclines alter calcium flux in DRG neurons through mechanisms involving extracellular calcium, TRPA1, and mitochondrial ROS.

This study shows that minocycline reduces chronic pain in male sickle cell disease mice via microglia and microbiome changes, but not in females.

The paper identifies an adipose-complement-lipid axis that systemically regulates sensory neuron sensitization, explaining pain-structure discordance in obesity-associated osteoarthritis.

This study shows that lifelong hydroxyurea treatment reduces chronic pain in sickle cell disease mice by decreasing immune activity and reversing TRPA1 sensitization.

This study shows that BDNF contributes to activity-induced muscle pain in male mice but not female mice, with no sex differences in BDNF expression changes.

A selective androgen receptor modulator microparticle formulation alleviates widespread muscle pain in male and female mice while being non-toxic.

This study shows that CaV1.3 knockout mice have motor learning deficits and impaired gait adaptation but normal anxiety, depression, and social behaviors.