The paper examines if deviations in brain aging (BrainAGE) predict alcohol initiation and use behavior in adolescents, finding a link with initiation but not with drinking patterns.

Developmental Cognitive Neuroscience · Aug 2, 2026Peer-reviewedNeuroscience

Longitudinal Neurocognitive Trajectories in a Large Cohort of Youth Who Use Cannabis: Combining Self-Report and Toxicology

Natasha E. Wade, Ryan M. Sullivan, Alexander L. Wallace, Rachel Visontay, Veronica Szpak, Krista M. Lisdahl, Marilyn Ann Huestis, Priscila Dib Gonçalves, Hollie R. Byrne, Louise R. Mewton, Joanna Jacobus, Susan Frances Tapert

The paper examines how cannabis use onset and THC/CBD exposure affect neurocognitive trajectories in adolescents using longitudinal data from the ABCD Study.

Neuropsychopharmacology · Apr 20, 2026Peer-reviewedNeuroscience

Structural Covariance Network Properties Predictive of Early Adolescent Alcohol Initiation

Hollie R. Byrne, Rachel Visontay, Emma Krogh Devine, Natasha E. Wade, Joanna Jacobus, Lindsay M. Squeglia, Louise R. Mewton

This study finds that structural covariance network properties in children aged 9-10 years predict early alcohol initiation before age 15.

bioRxiv · May 8, 2025 · PreprintNeuroscience

Interactions between mild traumatic brain injury and genetics perturb neuronal and glial pathways and networks relevant to learning and memory in ABCD study

Michael Cheng, Melody Mao, Wenjing Meng, Florin Vaida, Joanna Jacobus, Emily A. Troyer, Everett L. Delfel, Emily L. Dennis, Elisabeth A. Wilde, Tracy J. Abildskov, Nicola L. de Souza, Jeffrey E. Max, Xia Yang

The paper investigates the interaction between mild traumatic brain injury and genetics to identify pathway and network-level effects on learning and memory in adolescents using the ABCD cohort.

medRxiv · Mar 11, 2025 · PreprintGenetic & Genomic Medicine

Image processing and analysis methods for the Adolescent Brain Cognitive Development Study

Donald J. Hagler, Sean N. Hatton, M. Daniela Cornejo, Carolina Makowski, Damien A. Fair, Anthony Steven Dick, Matthew T. Sutherland, Betty Jo Casey, Deanna M. Barch, Michael P. Harms, Richard Watts, James Matthew Bjork, Hugh Garavan, Laura Hilmer, Christopher J. Pung, , Scott Peltier

The paper describes neuroimaging processing methods for the ABCD Study to extract brain phenotypes from multimodal imaging data.

NeuroImage · Aug 12, 2019Peer-reviewedNeuroscience