NeurosciencebioRxivPreprint
Seed-competent alpha-synuclein pathology in metachromatic leukodystrophy: the expanding spectrum of alpha-synucleinopathy in sphingolipidoses
Simona S. Ghanem, Jade I. Hawksworth, Searlait Thom…·Daniel Erskine
This study examines alpha-synuclein pathology in metachromatic leukodystrophy (MLD) brain tissue, finding seed-competent alpha-synuclein conformers in juvenile-onset cases, similar to Lewy body diseases.
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