Marina Jendrach

Altered Brain Energy Metabolism in the APPPS1 Alzheimer's Model during anesthesia: Integration of Experimental Data and In Silico Modeling

The paper investigates how anesthetic exposure affects brain energy metabolism in an Alzheimer's model, showing reduced oxidative metabolism and worsened potassium regulation in diseased tissue.

RNA promotes synapsin phase separation providing a platform for local translation

The paper shows RNA promotes synapsin phase separation, forming condensates that organize synaptic vesicles and enhance local translation.

Spermidine reduces neuroinflammation and soluble amyloid beta in an Alzheimer's disease mouse model

This study shows that spermidine reduces neuroinflammation and soluble amyloid beta in an Alzheimer's disease mouse model by targeting microglia and reducing inflammatory pathways.

The autophagy activator Spermidine ameliorates Alzheimer's disease pathology and neuroinflammation in mice

This study shows that Spermidine, an autophagy activator, reduces neuroinflammation and Aβ levels in AD-like mice by enhancing autophagy in microglia and astrocytes.