HY Li

This study identifies NYH0002 as a compound that blocks ILF2, leading to DNA breaks and lethality in cancers with specific genetic profiles.

This study benchmarks reverse docking pipelines using AlphaFold2 human proteome to predict drug-target interactions and off-target effects, finding that Glide_sfct (PS) performs best.

This paper demonstrates that conventional ML can achieve high accuracy in virtual screening with proper data and representation, outperforming deep learning methods.

This study shows SRRM2 forms biomolecular condensates and regulates alternative splicing, affecting innate immunity and cell homeostasis through specific splice isoforms.