Author

Yi Chieh Lim

Nanyang Technological UniversityORCID 0000-0003-1261-5419Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Anthony Robert WhiteiD· 1 shared Antonietta NotaroiD· 1 shared Benjamin LebeauiD· 1 shared C Soh· 1 shared Carla Cuní‐LópeziD· 1 shared Cheng-Gee KohiD· 1 shared Christine Cong GuoiD· 1 shared Hazel QuekiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Anthony Robert WhiteORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 21, 2025

ILF2 blockade suppresses helicase-mediated R-loop resolution to induce lethality in homologous recombination-deficient cancers

Yi Chieh Lim, Soak Kuan Lai, Ru Yang…·HY Li

This study identifies NYH0002 as a compound that blocks ILF2, leading to DNA breaks and lethality in cancers with specific genetic profiles.

DOI 10.1101/2025.05.21.655390

humanexperimental assay

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NeuroscienceJournal of NeuroinflammationPeer-reviewedFeb 28, 2022

ALS monocyte-derived microglia reveal cytoplasmic TDP-43 accumulation, DNA damage, and cell-specific impairment of phagocytosis associated with disease progression.

Hazel Quek, Carla Cuní‐López, Romal Stewart…·Anthony Robert White

This paper develops a method to generate monocyte-derived microglia from ALS patient blood, revealing functional impairments and pathological features associated with disease progression.

106 citationstop 1%

humanexperimental assay

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