Nikhil Gupta

This study examines changes in neuronal activation in the somatosensory and insular cortices during the transition from acute to chronic neuropathic pain.

This study compares CRISPR knockout and interference methods using single-cell RNA sequencing to evaluate their strengths in functional genomics.

The paper develops a scarless conditional sgRNA system using endogenous RNA processing to enable precise temporal control of genome editing with improved efficiency and fidelity.

The paper benchmarks CRISPR sgRNA design algorithms and creates smaller, efficient libraries for loss-of-function screens.

The paper identifies new regulators of germline genes and 2-cell like cell state through a genome-wide CRISPR knock-out screen in mouse ES cells.