Karl F. Herold

This study identifies a volatile anaesthetic binding site in voltage-gated sodium channels, showing it modulates channel function and reduces neuronal excitability.

This paper genetically engineers K2P channels to be activated by rapamycin or its analogs, enabling chemogenetic control of cellular membrane potential.

This study shows fast-acting antidepressants like ketamine trigger BDNF release from presynaptic terminals in mouse hippocampal neurons, leading to structural plasticity in CA3 pyramidal neurons.

This study investigates how sevoflurane affects Nav1.3 sodium channels in developing neurons, showing voltage-dependent inhibition and altered inactivation properties.