Jimcy Platholi

This study shows increased Nav1.3 expression in early-stage 5xFAD mice leads to CA3 hyperexcitability, suggesting Nav1.3 as a target for AD intervention.

The paper uses electron microscopic immunocytochemistry to map the subcellular localization of D1R and D2R in the mouse hippocampus, revealing distinct synaptic and non-synaptic distributions.

This study shows fast-acting antidepressants like ketamine trigger BDNF release from presynaptic terminals in mouse hippocampal neurons, leading to structural plasticity in CA3 pyramidal neurons.

This study investigates how sevoflurane affects Nav1.3 sodium channels in developing neurons, showing voltage-dependent inhibition and altered inactivation properties.

This study shows that perimenopause increases Aβ aggregation and glial activation in specific hippocampal regions in female 5xFAD mice, but not cognitive deficits.

The paper shows that a BDNF polymorphism (Val66Met) leads to persistent depression of excitatory synaptic transmission after isoflurane exposure in mice.