Author

Debra A. Wadford

California Department of Public HealthORCID 0000-0002-8630-427XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:experimental assay· 2 Research Focus:variant calling· 2 Organism:virus· 2 Assay:whole-genome sequencing· 2 Organism:human· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

John BelliD· 3 shared Adriano de Bernardi SchneideriD· 1 shared Aine Niamh O’TooleiD· 1 shared Alex Espinosa· 1 shared Amy L. KistleriD· 1 shared Andreas S. PuschnikiD· 1 shared Angela M. DetweileriD· 1 shared Angie S. HinrichsiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersGenomics

John BellORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GenomicsPLoS PathogensPeer-reviewedNov 10, 2025

Genomic and epidemiologic characteristics of SARS-CoV-2 persistent infections in California, January 2021 - July 2023

John Bell, Jesse Elder, Rahil Ryder…·Debra A. Wadford

This study identifies and characterizes 69 SARS-CoV-2 persistent infections in California using genomic and epidemiologic data, revealing demographic differences and mutations linked to immune evasion and variant emergence.

DOI 10.1371/journal.ppat.1013365

humanwhole-genome sequencing

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BioinformaticsVirus EvolutionPeer-reviewedJan 1, 2024

SARS-CoV-2 lineage assignments using phylogenetic placement/UShER are superior to pangoLEARN machine learning method

Adriano de Bernardi Schneider, Michelle Su, Angie S. Hinrichs…·Russell B Corbett-Detig

This study compares pangoLEARN and pUShER for SARS-CoV-2 lineage assignment, finding pUShER more stable and accurate across pangolin versions.

17 citationstop 4%

viruswhole-genome sequencing

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Molecular BiologybioRxivPreprintAug 25, 2020

Identification of a polymorphism in the N gene of SARS-CoV-2 that adversely impacts detection by a widely-used RT-PCR assay

Manu Vanaerschot, Sabrina A Mann, James T. Webber…·Emily D. Crawford

The paper identifies a SARS-CoV-2 N gene polymorphism that reduces RT-PCR assay sensitivity and emphasizes the need for multi-target testing.

11 citations

virusexperimental assay

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