Author

Cristina Calvo‐González

Consejo Superior de Investigaciones CientíficasORCID 0000-0002-8634-1978Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Achraf Hibot· 1 shared Alice ZuiniD· 1 shared Bernat CrosasiD· 1 shared Blanca D. López‐AyllóniD· 1 shared Cristina Benítez‐RodrígueziD· 1 shared Erika ZoddaiD· 1 shared Jaime Rubio‐MartíneziD· 1 shared María Dolors PujoliD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Achraf Hibot

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1 paper

Recent·Most cited

Induction of the inflammasome by the SARS-CoV-2 accessory protein ORF9b, abrogated by small-molecule ORF9b homodimerization inhibitors

Erika Zodda, Mònica Pons, Natàlia DeMoya‐Valenzuela, Cristina Calvo‐González, Cristina Benítez‐Rodríguez, Blanca D. López‐Ayllón, Achraf Hibot, Alice Zuin, Bernat Crosas, Marta Cascante, María Montoya, María Dolors Pujol, Jaime Rubio‐Martínez, Timothy M. Thomson

This study shows that SARS-CoV-2's ORF9b protein activates inflammasomes and caspase-1, and small molecules inhibiting its homodimerization reduce inflammation and restore interferon signaling.

Journal of Medical Virology · Feb 1, 2025Peer-reviewedMicrobiology