Shamik Sen

This paper develops glycocalyx-targeting hydrogels that enhance fibroblast regeneration in diabetic wounds by reversing pathological glycocalyx thickening and improving wound closure.

This study shows lipid droplets modulate amylin aggregation and β-cell stress by controlling its conformational changes and interaction pathways.

The paper shows that nuclear compression-induced DNA damage drives mESC differentiation via ATR-dependent Lamin A/C regulation.

This study shows that amylin aggregates faster on fibrillar collagen, leading to β-cell death and dysfunction, which accelerates diabetic progression.

This paper develops a hybrid nanocomposite for targeted topical delivery of resveratrol in psoriasis management, showing improved skin penetration, safety, and therapeutic efficacy.

This paper develops a hybrid nanoparticle-hydrogel system for psoriasis treatment, showing improved drug delivery and reduced PASI scores in vivo.

This study shows that CD44/Integrin β1 association enables faster cell motility on HA substrates by forming smaller, weaker focal adhesions.

This paper develops eugenol-loaded lipid nanoparticles in hydrogels to treat psoriasis by reducing oxidative stress and inflammation, showing significant improvement in psoriasis symptoms.

This study identifies Fmn2 as a molecular clutch that regulates growth cone motility by coupling actin dynamics to the extracellular matrix through point contact adhesion complexes.

This study identifies two distinct invasion mechanisms in drug-resistant ovarian cancer cells, both regulated by myosin IIB, with protease-dependent and protease-independent modes observed in cisplatin-resistant and dual-resistant cells respectively.