Author

Gautam Kannan

Indian Institute of Technology Bombay

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Akash Kumar JhaiD· 2 shared Ashutosh KumariD· 2 shared Md Asrafuddoza HazariiD· 2 shared Shamik SeniD· 2 shared Farhin SultanaiD· 1 shared Hamim ZafariD· 1 shared Musale Krushna PavaniD· 1 shared Prasenjit BhaumikiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Akash Kumar JhaORCID

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2 papers

Recent·Most cited

Lipid Droplets Direct Amyloid Assembly and β-Cell Stress through Interfacial Control of Amylin Aggregation

Akash Kumar Jha, Md Asrafuddoza Hazari, Sneha Singh, Gautam Kannan, Shamik Sen, Ashutosh Kumar

This study shows lipid droplets modulate amylin aggregation and β-cell stress by controlling its conformational changes and interaction pathways.

bioRxiv · Jun 16, 2026 · PreprintCell Biology

Faster amylin aggregation on fibrillar collagen hastens diabetic progression through β cell death and loss of function

Md Asrafuddoza Hazari, Gautam Kannan, Subrata Dasgupta, Musale Krushna Pavan, Akash Kumar Jha, Farhin Sultana, Soumya Ranjan Pujahari, Simran Singh, Sarbajeet Dutta, Sai Prasad Pydi, Sankhadeep Dutta, Hamim Zafar, Prasenjit Bhaumik, Ashutosh Kumar, Shamik Sen

This study shows that amylin aggregates faster on fibrillar collagen, leading to β-cell death and dysfunction, which accelerates diabetic progression.

Journal of the American Chemical Society · Apr 29, 2025Peer-reviewedBiophysics