Author

Shuangyu Li

University of California, IrvineORCID 0000-0002-8651-1148Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:multiome· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Lindsey V. SolesiD· 2 shared Lusong TianiD· 2 shared Marielle Cárdenas Valdez· 2 shared Yongsheng ShiiD· 2 shared Yoseop YooniD· 2 shared Angela M YuiD· 1 shared Erik AlvstadiD· 1 shared Fangyuan DingiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersMolecular Biology

Lindsey V. SolesORCID

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2 papers

Recent·Most cited

Molecular BiologyGenes & DevelopmentPeer-reviewedJul 1, 2026

The competition between splicing and 3' processing shapes the human transcriptome

Lindsey V. Soles, Shuangyu Li, Liang Liu…·Yongsheng Shi

The paper shows that splicing and 3' processing compete to shape the human transcriptome, with splicing inhibition activating 3' processing and vice versa.

4 citations

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologyMolecular CellPeer-reviewedApr 1, 2025

A nuclear RNA degradation code for eukaryotic transcriptome surveillance

Lindsey V. Soles, Liang Liu, Xudong Zou…·Yongsheng Shi

The paper identifies a nuclear RNA degradation code (NRDC) that recognizes transcripts with both a 5' splice site and a poly(A) junction, leading to their degradation and contributing to disease.

32 citationstop 4%

humanmultiome

𝕏 PostBluesky