Author
University of California, IrvineORCID 0009-0005-8916-4259Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Lindsey V. Soles, Shuangyu Li, Liang Liu…·Yongsheng Shi
The paper shows that splicing and 3' processing compete to shape the human transcriptome, with splicing inhibition activating 3' processing and vice versa.
Lusong Tian, Liang Liu (50022), Yoseop Yoon…·Yongsheng Shi
This study identifies LENG8 as a conserved RNA nuclear retention factor that prevents misprocessed mRNAs and noncoding RNAs from being exported, ensuring proper nuclear quality control.
Lindsey V. Soles, Liang Liu, Xudong Zou…·Yongsheng Shi
The paper identifies a nuclear RNA degradation code (NRDC) that recognizes transcripts with both a 5' splice site and a poly(A) junction, leading to their degradation and contributing to disease.