Author

Maëlle Givelet

InsermORCID 0000-0002-8658-1277Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:ChIP-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Pierre FouchetiD· 3 shared Clémentine Lapoujade· 2 shared Ahmed ZiyyatiD· 1 shared Alban Lermine· 1 shared Alberto de la IglesiaiD· 1 shared Anne‐Sophie GilleiD· 1 shared Audrey Michaud· 1 shared Catherine PatratiD· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersDevelopmental Biology

Pierre FouchetORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintDec 21, 2023

Characterization and hierarchy of the spermatogonial stem cell compartment in human spermatogenesis by spectral cytometry using a 16-colors panel

Clémentine Lapoujade, M. Blanco, Maëlle Givelet…·Pierre Fouchet

The paper identifies novel markers of human spermatogonial stem cells using spectral cytometry and defines their hierarchy in spermatogenesis.

DOI 10.1101/2023.12.21.572912

humanbulk RNA-seq

Molecular BiologyEMBO ReportsPeer-reviewedApr 26, 2023

The histone methyltransferase DOT1L regulates chromatin reorganization and gene expression during the postmeiotic differentiation of male germ cells

Mélina Blanco, Laïla El Khattabi, Clara Gobé…·Julie Cocquet

This study shows that DOT1L regulates chromatin reorganization and gene expression in male germ cells, leading to fertility defects in its absence.

22 citationstop 4%

mouseproteomics

Developmental BiologyNature CommunicationsPeer-reviewedAug 26, 2019

EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells

Roberta Ragazzini, Raquel Pérez-Palacios, Irem H. Baymaz…·Raphaël Margueron

This study identifies EZHIP as a novel cofactor of PRC2 that limits its activity in germ cells, leading to altered H3K27me2/3 deposition and impaired fertility in female mice.

107 citationstop 3%