Developmental BiologyNature CommunicationsPeer-reviewed
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells
Roberta Ragazzini, Raquel Pérez-Palacios, Irem H. Baymaz…·Raphaël Margueron
This study identifies EZHIP as a novel cofactor of PRC2 that limits its activity in germ cells, leading to altered H3K27me2/3 deposition and impaired fertility in female mice.