Author

Elizabeth Wei-Chia Luo

California Institute of TechnologyORCID 0000-0002-8663-0446Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:machine learning (classical)· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Gerard C. L. WongiD· 2 shared Haleh AlimohamadiiD· 2 shared Kelsey A NoldeniD· 2 shared Liting DuaniD· 2 shared R. Blake HilliD· 2 shared Michelle W. LeeiD· 1 shared Rena YangiD· 1 shared Shivam GuptaiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersBiophysics

Gerard C. L. WongORCID

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2 papers

Recent·Most cited

Drp1 Proteins Released from Hydrolysis-driven Scaffold Disassembly Trigger Nucleotide-dependent Membrane Remodeling to Promote Scission

Elizabeth Wei-Chia Luo, Kelsey A Nolden, Haleh Alimohamadi, Michelle W. Lee, Liting Duan, R. Blake Hill, Gerard C. L. Wong

The paper investigates the mechanism of mitochondrial fission by Drp1, showing that GTP hydrolysis enables free Drp1 to induce membrane negative Gaussian curvature, promoting scission.

Journal of the American Chemical Society · Jul 8, 2025Peer-reviewedBiophysics

Dynamins combine mechano-constriction and membrane remodeling to enable two-step mitochondrial fission via a snap-through instability.

Haleh Alimohamadi, Elizabeth Wei-Chia Luo, Xiaoying Liu, Wasi Iqbal, Rena Yang, Shivam Gupta, Kelsey A Nolden, Taraknath Mandal, R. Blake Hill, Liting Duan, Gerard C. L. Wong

This study shows how dynamin proteins use mechano-constriction and membrane curvature to drive mitochondrial fission through a snap-through instability.

Journal of the American Chemical Society · Jul 8, 2025Peer-reviewedBiophysics