Virginia M. S. Ruetten

The paper identifies a neuron-glia circuit in zebrafish that anticipates hypoxia by integrating behavioral intent and physiological state to prevent internal oxygen depletion.

This study tracks the development of heart-brain circuits in larval zebrafish, revealing three stages of functional maturation involving vagal motor, sympathetic, and sensory pathways.

The paper introduces WHOLISTIC, a method to image cellular activity across all organs of a vertebrate, revealing body-wide circuits and responses to stimuli.

FishExplorer integrates multimodal brain data from larval zebrafish to enable circuit analysis and hypothesis generation.

AQuA2 quantifies molecular spatiotemporal signals from live imaging data by decomposing complex datasets into signaling events, demonstrating applications across biosensors and cell types.

The paper develops an all-optical system to study whole-brain neuronal dynamics during gut interoception in zebrafish, revealing how nutrient delivery and sensory stimuli are encoded across brain regions.