Sujatha Narayan

3D-MAESTRO automates processing of large-scale volumetric brain microscopy data, enabling scalable and reproducible analysis of mouse brain structures.

Two-photon optical backfills of pan-neuronal photoactivatable GFP in larval zebrafish yield an estimated 1,300 spinal-projecting neurons per larva across hindbrain, midbrain and diencephalon, with tentative homologies to mammalian nuclei.

The paper shows how instructive inputs during a critical period shape neural circuits to enable effective credit assignment in learning.

The paper identifies a neuron-glia circuit in zebrafish that anticipates hypoxia by integrating behavioral intent and physiological state to prevent internal oxygen depletion.

This study identifies stk32a as a conserved sleep regulator that links neuropeptidergic signaling to sleep homeostasis by suppressing sensory and motor systems in zebrafish and mice.

The paper develops WARP, a platform integrating neuronal activity and gene expression data in zebrafish brains, revealing functional roles of molecularly defined cell populations and their activity correlations.

The paper shows that astrocyte activity drives brainwide changes in sensory, integrative, and motor computations during a passive state in zebrafish.

The paper uses voltage imaging to show how serotonergic neurons in the raphe encode action outcomes and modulate motor vigor during learning in larval zebrafish.

The paper develops a toolkit of transgenic mouse lines and enhancer AAVs for selective targeting of cortical cell populations using transcriptomic and epigenomic data.

The paper shows norepinephrine induces astroglial purinergic signaling that suppresses behavior through adenosine receptor activation in zebrafish.

The paper develops fast and sensitive GCaMP indicators for neural activity imaging, achieving ultra-fast kinetics and high sensitivity.

The paper shows ketamine suppresses futility-induced passivity in zebrafish by modulating astroglial calcium through norepinephrine signaling.

The paper identifies a brainstem circuit in larval zebrafish that integrates optic flow to maintain positional homeostasis by modulating cerebellar activity.

The paper develops cell body-targeted calcium indicators to improve signal fidelity in one-photon imaging of neural activity in live mice and zebrafish.

The paper introduces improved red calcium indicators that match the sensitivity of GFP-based indicators, enabling better in vivo neural activity imaging.