Sandra Zakrzewska

This study shows that RcSxph from American bullfrogs can counteract saxitoxin poisoning in mice by binding the toxin, validating its role as a toxin sponge.

This study identifies saxiphilin as a toxin sponge that binds multiple C13-modified saxitoxin congeners, revealing structural adaptability and conformational plasticity in toxin-protein interactions.

This paper identifies the structural basis for saxitoxin congener binding and neutralization by saxiphilins, showing how these proteins sequester toxins and reverse sodium channel blockage.