Zhou Chen

This study shows that RcSxph from American bullfrogs can counteract saxitoxin poisoning in mice by binding the toxin, validating its role as a toxin sponge.

This study identifies saxiphilin as a toxin sponge that binds multiple C13-modified saxitoxin congeners, revealing structural adaptability and conformational plasticity in toxin-protein interactions.

The paper identifies BAP1 as a deubiquitinase that stabilizes SPIN4 by counteracting degradation mediated by DCAF16.

This paper identifies the structural basis for saxitoxin congener binding and neutralization by saxiphilins, showing how these proteins sequester toxins and reverse sodium channel blockage.

This study introduces a platform to map reactive cysteines on MHC-I-bound peptides and shows interferon-gamma increases reactivity at position 8 of 9-mer antigens.

The paper demonstrates intrareceptor inhibition in mosquito odorant receptors through electrophysiological and behavioral studies.