Lauri J. Tuominen

Blunted fear-evoked striatal dopamine release in individuals with a family history of psychosis

The paper investigates dopamine release during fear conditioning in individuals with and without a family history of psychosis, finding reduced dopamine release in relatives despite normal learning, supporting the chaotic dopamine hypothesis.

Inter-individual variability of neurotransmitter receptor and transporter density in the human brain

This study quantifies inter-individual variability in PET-estimated receptor and transporter density across 12 neurotransmitter systems in the human brain.

Physical exercise and brain network dynamics: reduction of frontoparietal-striatal connectivity following 1 hour of aerobic cycling

This study examines changes in brain network dynamics after 60 minutes of aerobic cycling, finding reduced striato-frontoparietal connectivity.

Molecular, physiological and functional features underlying cortical thinning related to antipsychotic medication use

This study identifies molecular, physiological, and functional mechanisms underlying antipsychotic-related cortical thinning using data from patients with early psychosis and a large meta-analysis.

Mapping neurotransmitter systems to the structural and functional organization of the human neocortex

Neurotransmitter receptor/transporter PET maps (19 targets, 1239 healthy participants) align with connectomes, explain MEG power, and track cognitive gradients and cortical thinning in 13 disorders.

Correspondence between gene expression and neurotransmitter receptor and transporter density in the human brain

The paper examines the relationship between gene expression and neurotransmitter receptor/transporter density in the human brain using PET and autoradiography, finding poor spatial correspondence except for four specific receptors.

Mesolimbic opioid-dopamine interaction is disrupted in obesity but recovered by weight loss following bariatric surgery

This study shows that bariatric surgery restores disrupted opioid-dopamine interaction in the ventral striatum of obese individuals.

Cerebral grey matter density is associated with neuroreceptor and neurotransporter availability: A combined PET and MRI study

Magia: Robust automated image processing and kinetic modeling toolbox for PET neuroinformatics

Magia automates PET brain data processing, producing outcome measures consistent with manual methods despite anatomical differences in reference regions.

The Shared Genetic Basis of Educational Attainment and Cerebral Cortical Morphology

This study identifies shared genetic factors between educational attainment and cerebral cortical morphology using UK Biobank data and novel statistical methods.