Alysa E. Doyle

Inflections in adolescent cortical maturation signal psychopathology risk

The paper shows that differences in adolescent cortical maturation patterns predict psychiatric symptoms, with early maturing sensory regions linked to symptoms four years before their onset.

Uncovering and mitigating bias in large, automated MRI analyses of brain development

This paper identifies and addresses quality-related biases in structural MRI analyses of children by improving automated quality control methods.

Analysis of structural brain asymmetries in Attention-Deficit/Hyperactivity Disorder in 39 datasets

This study analyzes structural brain asymmetries in ADHD using 39 datasets, finding small effects that do not meet study-wide significance thresholds.

Evidence for Similar Structural Brain Anomalies in Youth and Adult Attention-Deficit/Hyperactivity Disorder: A Machine Learning Analysis

This study uses machine learning to show that structural brain anomalies in ADHD are similar in children and adults, supporting continuity of the disorder's pathophysiology.

Shared genetic background between children and adults with attention deficit/hyperactivity disorder

This study identifies nine new genetic loci associated with ADHD and shows shared genetic architecture between childhood and adult ADHD.

Subcortical brain volume, regional cortical thickness and cortical surface area across attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and obsessive-compulsive disorder (OCD): findings from the ENIGMA-ADHD, -ASD, and -OCD working groups

This study compares structural brain differences across ADHD, ASD, and OCD using MRI data from multiple cohorts, finding disorder-specific alterations in brain volume and cortical thickness.

The Shared Genetic Basis of Educational Attainment and Cerebral Cortical Morphology

This study identifies shared genetic factors between educational attainment and cerebral cortical morphology using UK Biobank data and novel statistical methods.

A genetic investigation of sex bias in the prevalence of attention deficit hyperactivity disorder

This study investigates genetic mechanisms underlying sex bias in ADHD prevalence using genome-wide data and finds no mean polygenic burden difference across sexes but increased risk in female siblings and comorbid conditions.