Lazar Fleysher

Deep brain stimulation induces white matter remodeling and functional changes to brain-wide networks

This study shows that deep brain stimulation remodels white matter and alters brain-wide functional connectivity in macaques, contributing to its therapeutic effects.

Pharmacological modulation of dopamine D1 and D2 receptors reveals distinct neural networks related to probabilistic learning in non-human primates.

This study examines the effects of D1 and D2 receptor antagonists on probabilistic learning and brain connectivity in macaques, revealing distinct neural networks associated with learning and motivation.

Ventrolateral prefrontal cortex in macaques guides decisions in different learning contexts

This study investigates how vlPFC activity and connectivity guide decision-making in different learning contexts using rhesus macaques.

Brain Charts for the Rhesus Macaque Lifespan

This study creates normative brain growth charts for rhesus macaques across their lifespan using MRI data, revealing developmental milestones and cross-species comparisons with humans.

The neural basis of resting-state fMRI functional connectivity in fronto-limbic circuits revealed by chemogenetic manipulation

This study uses chemogenetic manipulation in macaques to show that activating inhibitory DREADDs in the amygdala increases resting-state fMRI functional connectivity between the amygdala and ventrolateral prefrontal cortex.

Resting-state fMRI-based screening of deschloroclozapine in rhesus macaques predicts dosage-dependent behavioral effects

This study uses resting-state fMRI to screen deschloroclozapine in rhesus macaques, showing dosage-dependent changes in brain connectivity and behavioral effects.