J. Megan Fredericks

This study investigates the role of amygdala to ventrolateral prefrontal cortex (vlPFC) projections in contingent learning by inhibiting these connections in macaques and observing effects on reward signaling and choice memory.

The paper identifies cell type-specific enhancers for the DLPFC in NHPs using single nucleus RNA-Seq and ATAC-Seq, validates them with AAV injections, and demonstrates functional expression in specific neuron types.

The paper uses MAPseq to analyze BLA neuron projections in macaques, finding that many neurons project to multiple brain regions and form structured networks.

This study uses resting-state fMRI to screen deschloroclozapine in rhesus macaques, showing dosage-dependent changes in brain connectivity and behavioral effects.