Author

Valentina Zorzini

KU LeuvenORCID 0000-0002-8727-309XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Rodrigo U. GallardoiD· 2 shared Brajabandhu PradhaniD· 1 shared Chris UlensiD· 1 shared Frédéric RousseauiD· 1 shared Gabriele OrlandoiD· 1 shared Jana KuschiD· 1 shared Jessica Matos Kleiz-FerreiraiD· 1 shared Jessica S. WagneriD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Rodrigo U. GallardoORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 14, 2025

Structural basis for gating inhibition by the cytoplasmic domain in HCN1 channels

Valentina Zorzini, Jessica Matos Kleiz-Ferreira, Marijke Brams…·Chris Ulens

This study uses cryo-EM to analyze HCN1 channel variants, revealing structural differences in cAMP sensitivity and auto-inhibition mechanisms between HCN1 and HCN2 isoforms.

DOI 10.1101/2025.10.14.682313

cryo-EMexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintJul 17, 2025

Atomic structures of medin and Aβ fibrils reveal polymorphic remodeling in mixed amyloid systems

Brajabandhu Pradhan, Senthil T. Kumar, Jessica S. Wagner…·Joost W. H. Schymkowitz

This study determines the cryo-EM structures of Aβ40 and medin fibrils in vitro, revealing polymorphic remodeling and mixed amyloid interactions.

3 citations

humancryo-EM

𝕏 PostBluesky