Author

Jessica Matos Kleiz-Ferreira

KU LeuvenORCID 0000-0003-0168-825XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Chris UlensiD· 2 shared Marijke BramsiD· 2 shared Andrew QuigleyiD· 1 shared Casey I. GallagheriD· 1 shared Daniel BertrandiD· 1 shared Jana KuschiD· 1 shared Mieke NysiD· 1 shared Peter J. HarrisoniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Chris UlensORCID

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedMar 13, 2026

Structure of a pH-sensitive pentameric ligand-gated ion channel from the Sarcoptes scabies mite

Jessica Matos Kleiz-Ferreira, Marijke Brams, Peter J. Harrison…·Chris Ulens

This study determines the structure of a pH-sensitive ion channel from the scabies mite and shows how ivermectin modulates its activity through pH-dependent conformational changes.

2 citations

cryo-EMexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintOct 14, 2025

Structural basis for gating inhibition by the cytoplasmic domain in HCN1 channels

Valentina Zorzini, Jessica Matos Kleiz-Ferreira, Marijke Brams…·Chris Ulens

This study uses cryo-EM to analyze HCN1 channel variants, revealing structural differences in cAMP sensitivity and auto-inhibition mechanisms between HCN1 and HCN2 isoforms.

DOI 10.1101/2025.10.14.682313

cryo-EMexperimental assay

𝕏 PostBluesky