Author
VIB-KU Leuven Center for Brain & Disease ResearchORCID 0000-0003-1584-3564Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Annelore Vandendriessche, Teresa Mendes Maia, Frank Timmermans…·Amélie Dendooven
The paper uses proteomics to show increased ECM remodeling and complement activation in cardiac ATTR amyloidosis.
Valentina Zorzini, Jessica Matos Kleiz-Ferreira, Marijke Brams…·Chris Ulens
This study uses cryo-EM to analyze HCN1 channel variants, revealing structural differences in cAMP sensitivity and auto-inhibition mechanisms between HCN1 and HCN2 isoforms.
Brajabandhu Pradhan, Senthil T. Kumar, Jessica S. Wagner…·Joost W. H. Schymkowitz
This study determines the cryo-EM structures of Aβ40 and medin fibrils in vitro, revealing polymorphic remodeling and mixed amyloid interactions.
Anita Pras, Bert Houben, Francesco A. Aprile…·Ellen A. A. Nollen
The paper identifies MOAG-4/SERF as modifiers of amyloid formation through charge complementation, showing that charge interactions drive protein aggregation and toxicity.