George Wanes

The paper uses a simulation model to show how ribosome structure and molecular sterics guide tmRNA translocation during trans-translation.

This study identifies bL27's role in preventing tmRNA from interfering with protein synthesis during trans-translation in bacteria.

The paper develops a theoretical model to study how ionic interactions influence subunit rotation in the yeast ribosome, showing that ion concentration changes significantly affect the energy landscape and kinetics of rotation.

The paper investigates the role of Mettl15 and Mettl17 in mitoribosome assembly, revealing their cooperative mechanism in transitioning from early to late stages of small subunit formation.

This study identifies how RORγt mutations affect gene activation by altering chromatin binding modes, explaining context-dependent autoimmunity and host defense outcomes.