Author

Michael Takla

University of CambridgeORCID 0000-0002-8779-0118Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alexander S. AnisimoviD· 1 shared Anne SimonseniD· 1 shared David Chaim RubinszteiniD· 1 shared David H. MeyeriD· 1 shared Evandro Fei FangiD· 1 shared Guang Xiu LuiD· 1 shared HAN-MING SHENiD· 1 shared John P. LabbadiaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Alexander S. AnisimovORCID

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1 paper

Recent·Most cited

ATG-18 drives longevity in an HLH-30-dependent manner

Tomas Schmauck‐Medina, Alexander S. Anisimov, David H. Meyer, Yue Hu, Zebo Huang, Yue Wu, Samuel J. Taylor, Michael Takla, Michael Robert MacArthur, Sarah Jayne Mitchell, Ruixue Ai, Anne Simonsen, Vidar Jensen, John P. Labbadia, HAN-MING SHEN, , Evandro Fei Fang

This study shows that ATG-18 overexpression extends C. elegans lifespan and improves stress resilience through the HLH-30 transcription factor, while also revealing a temporal-specific effect on heat stress survival.

bioRxiv · Jan 29, 2026 · PreprintMolecular Biology