Weiwei Yang

The paper identifies 5mC-selective deaminases and demonstrates their use in ultra-sensitive methylome sequencing at single-base resolution.

The paper identifies key players in the 2,6-diaminopurine biosynthesis pathway using metagenomic data from aquatic environments.

The paper applies Proxi-RIMS-seq2 to native microbiomes to identify m5C methylation motifs and their cognate methyltransferases, revealing over 1900 motifs including a novel 8-base recognition site.

The paper identifies new prokaryotic wH domain-containing endonucleases that sense adenine methylation in specific DNA contexts.

This study introduces MetaGPA, a framework linking metagenomic genetic data to functional phenotypes, and identifies a novel cytosine modification mechanism in DNA and RNA.