MicrobiologySignal Transduction and Targeted TherapyPeer-reviewed
Novel derivatives of BCV and (S)-HPMPA inhibit orthopoxviruses and human adenoviruses more potently than BCV
Yifan Zhang, Yanmin Wan, Cuiyuan Guo…·Wenhong Zhang
This study evaluates novel prodrugs based on (S)-HPMPA and (S)-HPMPC, finding that ODE-(S)-HPMPA formate is more potent against orthopoxviruses and adenoviruses than BCV, but less effective against HSV-1.
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