Author

Wenhong Zhang

Shanghai Medical College of Fudan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Microbiology· 6 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Assay:bulk RNA-seq· 3 Organism:E. coli· 3 Research Focus:host-pathogen & immune response· 3 Organism:bacteria (other)· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2

Frequent Co-Authors

Ying Zhang· 5 shared Nan Wu· 3 shared Peng Cui· 3 shared Shanshan Zhang· 3 shared Shuang Liu· 3 shared Jie Feng· 2 shared Wanliang Shi· 2 shared Yumeng Zhang· 2 shared

Activity by Year

2017-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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5 shared papersMicrobiology

Ying Zhang

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Phylogenomic screening reveals idsA2 loss conferring nitroimidazole cross-resistance in Mycobacterium tuberculosis

Yu Zhang, Xinchang Chen, Shiyong Wang, Qian Wu, Yuchang Di, Weifang Lin, Wenya Hua, Xuelian Zhang, Ning Jiang, Wenhong Zhang, Jiazhen Chen

A length- and mutation-load-corrected homoplasy screen of 1,813 MDR-TB genomes flags idsA2; its loss raises pretomanid MIC fourfold, delamanid and ethambutol twofold, via isoprenoid flux redirection.

bioRxiv · Oct 24, 2026 · PreprintPathology✦ In-depth digest

Identification of small regulatory RNAs involved in persister formation

Shanshan Zhang, Shuang Liu, Nan Wu, Wenhong Zhang, Ying Zhang

This study identifies seven small regulatory RNAs involved in type II persister formation in uropathogenic E. coli.

bioRxiv · Apr 30, 2018 · PreprintMicrobiology

Identification of novel genes including rpmF and yjjQ critical for Type II persister formation in Escherichia coli

Shuang Liu, Nan Wu, Shanshan Zhang, Yumeng Zhang, Wenhong Zhang, Ying Zhang

This study identifies novel genes critical for Type II persister formation in E. coli by analyzing transcriptome changes during persister emergence and abundance and validating their roles through knockout and overexpression experiments.

bioRxiv · Apr 30, 2018 · PreprintMicrobiology

Identification of Polynucleotide Phosphorylase (PNPase) in Escherichia coli Involved in Persister Formation

Nan Wu, Yumeng Zhang, Shanshan Zhang, Youhua Yuan, Shuang Liu, Peng Cui, Wenhong Zhang, Ying Zhang

This study identifies PNPase as a key regulator of persister formation in E. coli by negatively regulating the crp operon at the post-transcriptional level.

bioRxiv · Apr 30, 2018 · PreprintMicrobiology

Cycloserine for Treatment of Multidrug-Resistant Tuberculosis in China: A Retrospective Observational Study

Yang Li, Fei Wang, Limin Wu, Min Zhu, Guiqing He, Feng Sun, Qihui Liu, Xiaomeng Wang, Wenhong Zhang

This study evaluates cycloserine's efficacy and safety in treating MDR-TB in China, finding it improves outcomes for simple MDR-TB but not pre-XDR-TB or XDR-TB.

bioRxiv · Apr 25, 2018 · PreprintMicrobiology

Clofazimine targets essential nucleoid associated protein, mycobacterial integration host factor (mIHF), in Mycobacterium tuberculosis

Wanliang Shi, Shuo Zhang, Jie Feng, Peng Cui, Wenhong Zhang, Ying Zhang

This study identifies mIHF as the target of clofazimine in Mycobacterium tuberculosis, showing it inhibits DNA binding and gene expression, offering new insights into its mechanism of action.

bioRxiv · Sep 21, 2017 · PreprintMicrobiology

Identification of a Novel Gene argJ involved in Arginine Biosynthesis Critical for Persister Formation in Staphylococcus aureus

Rebecca Yee, Peng Cui, Tao Xu, Wanliang Shi, Jie Feng, Wenhong Zhang, Ying Zhang

This study identifies argJ, a gene involved in arginine biosynthesis, as critical for persister formation in S. aureus, with implications for developing new treatments for persistent infections.

bioRxiv · Mar 7, 2017 · PreprintMicrobiology