Author

Yifan Zhang

Broad InstituteORCID 0000-0002-3309-298XUnclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yifan Zhang7 papers · University of California San Diego

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:long-read sequencing· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Andrea Navarro TorresiD· 1 shared Anisha LaumasiD· 1 shared Chao QiuiD· 1 shared Cuiyuan Guo· 1 shared David Wollensak· 1 shared Fahui Dai· 1 shared Fei CheniD· 1 shared Gail SchoriD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Andrea Navarro TorresORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintNov 5, 2025

Generative Design of Cell Type-Specific RNA Splicing Elements for Programmable Gene Regulation

Xi Dawn Chen, Manson Jim, Mounica Vallurupalli…·Fei Chen

The paper introduces SPICE, a framework that uses splicing assays and generative design to create cell-specific gene regulation elements for research and therapy.

4 citations

𝕏 PostBluesky

MicrobiologySignal Transduction and Targeted TherapyPeer-reviewedApr 10, 2025

Novel derivatives of BCV and (S)-HPMPA inhibit orthopoxviruses and human adenoviruses more potently than BCV

Yifan Zhang, Yanmin Wan, Cuiyuan Guo…·Wenhong Zhang

This study evaluates novel prodrugs based on (S)-HPMPA and (S)-HPMPC, finding that ODE-(S)-HPMPA formate is more potent against orthopoxviruses and adenoviruses than BCV, but less effective against HSV-1.

16 citationstop 3%

humanexperimental assay

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