Bruno Guigas

This study shows that Bulevirtide increases plasma bile salt levels in mice, reducing inflammation in LPS-induced models and DSS-induced colitis.

Totum-448 reduces hepatic steatosis and inflammation in diet-induced MASLD mice without affecting body weight or microbiota.

This paper develops a chemoenzymatic method to precisely glyco-tag proteins, enabling the modification of therapeutic proteins with diverse glycans while maintaining their biological activity.

This study shows that early exercise training in mice worsens hepatic inflammation in early NAFLD, while late training does not, suggesting timing affects exercise benefits.