Charlotte F. Brzozowski

This study shows that α-synuclein aggregates in corticostriatal terminals impair glutamatergic transmission without causing neurodegeneration.

This study shows that aggregated α-synuclein impairs corticostriatal synaptic function and reduces synaptic density in mice, with some synapses showing increased volume.

This study investigates how α-synuclein aggregates in the basolateral amygdala affect synaptic structure and function in a mouse model of Parkinson's disease.

This study shows that inhibiting LRRK2 kinase activity increases α-synuclein presynaptic localization and anterograde axonal transport in neurons.