Author

Harshita Challa

University of Alabama at BirminghamORCID 0009-0003-4931-7105Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Assay:imaging· 1

Frequent Co-Authors

Charlotte F. BrzozowskiiD· 2 shared IGNACIO GALLARDO· 2 shared Laura A. Volpicelli‐DaleyiD· 2 shared Mark S. MoehleiD· 2 shared Michael MillettiD· 2 shared Dominic HalliD· 1 shared Douglas Nabert· 1 shared Douglas Narbert· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Charlotte F. BrzozowskiORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintAug 7, 2026

α-Synuclein aggregates in corticostriatal terminals impair glutamatergic transmission in the absence of neurodegeneration

Charlotte F. Brzozowski, Zoe N. Fokakis, Marissa A. Menard…·Laura A. Volpicelli‐Daley

This study shows that α-synuclein aggregates in corticostriatal terminals impair glutamatergic transmission without causing neurodegeneration.

DOI 10.64898/2026.08.03.742532

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintJan 29, 2025

Aggregated α-synuclein leads to corticostriatal synaptic dysfunction

Charlotte F. Brzozowski, Harshita Challa, Nolwazi Z. Gcwensa…·Mark S. Moehle

This study shows that aggregated α-synuclein impairs corticostriatal synaptic function and reduces synaptic density in mice, with some synapses showing increased volume.

1 citation

𝕏 PostBluesky