Author

Vijay Singh

University of Alabama at Birmingham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Neuroscience· 4 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1

Frequent Co-Authors

Laura A. Volpicelli‐DaleyiD· 3 shared Aakriti JainiD· 1 shared Andrew B. WestiD· 1 shared Andrew D. SauerbeckiD· 1 shared Anjali GargiD· 1 shared Armin BayatiiD· 1 shared Baraa A. HijaziD· 1 shared Charlotte F. BrzozowskiiD· 1 shared

Activity by Year

2021-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersNeuroscience

Laura A. Volpicelli‐DaleyORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Neural cell state modulation by PARK2 and dopaminergic neuroprotection by small molecule Parkin agonism

Yongxing Gong, Armin Bayati, Tyler Joseph Alban, Prerana Bangalore Parthasarathy, Fang Zhou, Vladimir Makarov, Yuhang Zhao, Chien‐Wen Su, Jackson G. Schumacher, Vijay Singh, Laura A. Volpicelli‐Daley, Wen Luo, Thomas M. Durcan, Shovan Dutta, Michael A. Schwarzschild, , Xiqun Chen

This study shows that Parkin is essential for neuronal differentiation and survival, and small molecule Parkin agonists like FB231 protect dopaminergic neurons in Parkinson's disease models.

bioRxiv · Apr 4, 2026 · PreprintNeuroscience

Impaired Functional Connectivity of Cortico-Amygdala Pathway Can Drive Social Behavior Deficits in Synucleinopathies

Wei Zhou, Samuel R. Daniels, Vijay Singh, Marissa A. Menard, Martha L. Escobar Galvis, Hong‐Yuan Chu

This study shows that -synuclein aggregation disrupts cortico-amygdala connectivity, leading to social behavior deficits in synucleinopathies, and that restoring this connection can rescue the behavior.

Neurobiology of Disease · Oct 13, 2024Peer-reviewedNeuroscience

Cortical synaptic vulnerabilities revealed in a α-synuclein aggregation model of Parkinson's disease

Saroj Kumar Sah, Andrew D. Sauerbeck, Jyoti Gupta, Dayana Pérez-Acuña, Jacob E. Reiber, Drèson L. Russell, Vijay Singh, Lamisa Musarat, Laura A. Volpicelli‐Daley, Michael J. Higley, Terrance T. Kummer, Thomas Biederer

This study identifies excitatory synapses as primary targets of α-synuclein aggregation in a Parkinson's disease mouse model, revealing spatial and temporal patterns of synaptic vulnerability.

bioRxiv · Jun 20, 2024 · PreprintNeuroscience

Identification and Characterization of Novel Metagenome Assembled Uncultivated Virus Genomes from Human Gut

Kanchan Bhardwaj, Niharika Niharika, Anjali Garg, Aakriti Jain, Mahesh Kumar, Manish Datt, Vijay Singh, Sudhanshu Vrati

The paper identifies and characterizes novel metagenome-assembled virus genomes from the human gut, revealing new species and functional genes.

bioRxiv · May 7, 2024 · PreprintGenomics

Inhibition of LRRK2 kinase activity promotes anterograde axonal transport and presynaptic targeting of α-synuclein

Charlotte F. Brzozowski, Baraa A. Hijaz, Vijay Singh, Nolwazi Z. Gcwensa, Kaela Kelly, Edward S. Boyden, Andrew B. West, Deblina Sarkar, Laura A. Volpicelli‐Daley

This study shows that inhibiting LRRK2 kinase activity increases α-synuclein presynaptic localization and anterograde axonal transport in neurons.

Acta Neuropathologica Communications · Nov 8, 2021Peer-reviewedNeuroscience